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autosomal dominant inheritance

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Definition

Autosomal dominant inheritance is a pattern of inheritance in which a single copy of a mutated gene on one of the autosomes (non-sex chromosomes) is sufficient to cause a particular trait or disorder. This means that an affected individual has a 50% chance of passing the mutated gene to each of their offspring, regardless of the child's sex. The trait or disorder typically appears in every generation, as affected individuals usually have at least one affected parent.

Synonyms

1

dominant inheritance

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autosomal dominant trait

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monogenic dominant inheritance

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single-gene dominant inheritance

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Mendelian dominant inheritance

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